Post-Doc Research Associate
University of North Carolina at Chapel Hill

Department:

Thurston Arthritis Res Center - 429201

12/03/2023

Yes

Postdoctoral Scholar

Post-Doc Research Associate

PDS004047

Full-Time Temporary

40

1

Chapel Hill, NC

North Carolina, US

Dependent Upon Qualifications and Experience

03/04/2024

12 Months

The UNC School of Medicine has a rich tradition of excellence and care. Our mission is to improve the health and wellbeing of North Carolinians, and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. We strive to promote faculty, staff, and learner development in a diverse, respectful environment where our colleagues demonstrate professionalism, enhance learning, and create personal and professional sustainability. We optimize our partnership with the UNC Health System through close collaboration and commitment to service.
OUR VISION
Our vision is to be the nation's leading public school of medicine. We are ranked 2nd in primary care education among all US schools of medicine and 5th among public peers in NIH research funding. Our Allied Health Department is home to five top-ranked divisions, and we are home to 18 top-ranked clinical and basic science departments in NIH research funding.
OUR MISSION
Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research.
Patient Care: We will promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond.
Education: We will prepare tomorrow's health care professionals and biomedical researchers by facilitating learning within innovative curricula and team-oriented interprofessional education. We will cultivate outstanding teaching and research faculty, and we will recruit outstanding students and trainees from highly diverse backgrounds to create a socially responsible, highly skilled workforce.
Research: We will develop and support a rich array of outstanding health sciences research programs, centers, and resources. We will provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our University to support outstanding research. We will foster programs in the areas of basic, translational, mechanistic, and population research.

The Phanstiel lab at UNC (http://phanstiel-lab.med.unc.edu/) has an open position for a computational postdoc to study the genetics of human disease. The successful candidate will analyze response QTLs (expression QTLs, splicing QTLs, chromatin accessibility QTLs, etc) as well as corresponding genomic data (Hi-C, CUT&RUN, phosphoproteomics, etc) in primary human cells to identify novel human disease risk variants and genes. They will also co-lead projects using massively parallel reporter assays (MPRA) to quantify the impacts of disease-related genetic variants. Finally, they will interact with nearby collaborators to plan and analyze functional follow-up experiments using CRISPR-based techniques applied to primary human cells grown in an ex vivo system. Hundreds of data sets have already been collected and are ready to be analyzed. Prior experience with some human genetic/genomic data sets (e.g. GWAS, QTL, Hi-C, ATAC, RNA-seq, etc) is preferred but not required.

Ph.D

PhD in Genetics, Biology, Computational Biology, or related field. Experience with computational analysis of genomic data.

Prior experience with some human genetic/genomic data sets (e.g. GWAS, QTL, Hi-C, ATAC, RNA-seq, etc).

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