Research Specialist A (Department of Neurosurgery)
University of Pennsylvania

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Posted Job TitleResearch Specialist A (Department of Neurosurgery)Job Profile TitleResearch Specialist AJob Description SummaryPlans and conducts basic experiments to meet research project objectives, with close supervision. Assists in performing laboratory experiments and clinical studies for product or material formulation and development. Daily management of laboratory tools, documentations and processes to ensure regulatory compliance and timely completion of project/program deliverables.Job Description

Our lab at The University of Pennsylvania is seeking an enthusiastic, dedicated, and highly motivated Research Specialist to assist with daily lab responsibilities and research projects. The focus of our lab's research is at the intersection of immunology, metabolism, and brain tumor biology. The primary goal of our translational research is to understand mechanisms of immune evasion by primary malignant brain tumors and skull base tumors to generate novel immune-based therapies. The specialist will be closely working with the Principal Investigator and other lab members on the collection and processing of patient tumor and blood samples, laboratory experiments using a wide array of techniques, and daily management of laboratory orders and maintenance.

The research specialist will work in a collaborative team on ongoing research projects involving patient specimen and mouse models. The research will involve work with a combination of high-dimensional single cell immune and genomic profiling, spectral flow cytometry, metabolomics, and advanced tumor organoid and mouse models. S/he will work cooperatively with laboratory members and collaborate with other groups (both laboratory and clinical) on campus. Ideally, the research specialist will develop a high level of independence with the ability to devise novel experiments and critically analyze projects.

Job responsibilities:

- Processing of patient tumor and blood specimen for banking and downstream experiments

- Single cell multi-omic analysis including single cell RNA sequencing and single nuclei RNA and ATAC sequencing

- Perform multi-dimensional flow cytometry

- Perform metabolomic experiments and analysis using mass spectrometry

- Perform co-culturing and stimulation experiments using in-vitro organoid models

- Potential future maintenance of mouse colony with tumor implantation, administration of therapy, tissue harvesting, and blood collection in mouse models

- Potential future involvement in analysis of patient samples from ongoing translational clinical trials.

While a general understanding/experience with immunology and metabolomic techniques is preferred, no prior experience in the above techniques is required. The Principal Investigator is committed to a longitudinal, dynamic mentorship model and will train the specialist in the above techniques. Additional responsibilities will include, but are not limited to: (1) assisting with writing standard laboratory/research operations documentations; (2) maintaining logs, laboratory reports/inventory, and ordering supplies. Highly motivated individuals will have the opportunity to expand their research portfolio through co-authorship on scientific manuscripts and will be encouraged to participate in educational/research conferences.

Qualifications:

Bachelor's Degree in Science or related field and 0 to 1 year of laboratory experience or an equivalent combination of education and experience required. Candidate must have strong organizational skills, good written and verbal communication skills and ability to learn new techniques and analytical methods. The ability to work in a collaborative environment.

This position is contingent on funding.

Job Location - City, StatePhiladelphia, PennsylvaniaDepartment / SchoolPerelman School of MedicinePay Range$36,368.00 - $51,750.00 Annual RateSalary offers are made based on the candidate's qualifications, experience, skills, and education as they directly relate to the requirements of the position, as well as internal and market factors and grade profile. Affirmative Action Statement
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.Special Requirements
Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.University Benefits

• Health, Life, and Flexible Spending Accounts: Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family's health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars.
• Tuition: Take advantage of Penn's exceptional tuition benefits. You, your spouse, and your dependent children can get tuition assistance here at Penn. Your dependent children are also eligible for tuition assistance at other institutions.
• Retirement: Penn offers generous retirement plans to help you save for your future. Penn's Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard.
• Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family-whatever your personal needs may be.
• Long-Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long-term care insurance to help you cover some of the costs of long-term care services received at home, in the community or in a nursing facility. If you apply when you're newly hired, you won't have to provide proof of good health or be subject to underwriting requirements. Eligible family members must always provide proof of good health and are subject to underwriting.
• Wellness and Work-life Resources: Penn is committed to supporting our faculty and staff as they balance the competing demands of work and personal life. That's why we offer a wide variety of programs and resources to help you care for your health, your family, and your work-life balance.
• Professional and Personal Development: Penn provides an array of resources to help you advance yourself personally and professionally.
• University Resources: As a member of the Penn community, you have access to a wide range of University resources as well as cultural and recreational activities. Take advantage of the University's libraries and athletic facilities, or visit our arboretum and art galleries. There's always something going on at Penn, whether it's a new exhibit at the Penn Museum, the latest music or theater presentation at the Annenberg Center, or the Penn Relays at Franklin Field to name just a few examples. As a member of the Penn community, you're right in the middle of the excitement-and you and your family can enjoy many of these activities for free.
• Discounts and Special Services: From arts and entertainment to transportation and mortgages, you'll find great deals for University faculty and staff. Not only do Penn arts and cultural centers and museums offer free and discounted admission and memberships to faculty and staff. You can also enjoy substantial savings on other goods and services such as new cars from Ford and General Motors, cellular phone service plans, movie tickets, and admission to theme parks.
• Flexible Work Hours: Flexible work options offer creative approaches for completing work while promoting balance between work and personal commitments. These approaches involve use of non-traditional work hours, locations, and/or job structures.
• Penn Home Ownership Services: Penn offers a forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia, which can be used for closing costs or home improvements.
• Adoption Assistance: Penn will reimburse eligible employees on qualified expenses in connection with the legal adoption of an eligible child, such as travel or court fees, for up to two adoptions in your household.

To learn more, please visit: https://www.hr.upenn.edu/PennHR/benefits-pay

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